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Titlebook: Ergot Alkaloids and Related Compounds; B. Berde,H. O. Schild (Emeritus Professor of Pharm Book 1978 Springer-Verlag Berlin · Heidelberg 19

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Toxicologic Considerations,eflected in some of the names given to the early compounds extracted, e.g., chrysotoxin, secalintoxin (. and ., 1907). One such name persists even today: ergotoxine. The purpose of this chapter is to review the information available on the toxicity of chemically defined ergot derivatives, both in an
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Toxicologic Considerations,imals and in man. The topics chosen are: Systemic Toxicity, Effects on Reproductive Processes, Potential Genetic Effects, and Interactions. The nomenclature for ergot derivatives used is that given in Chapter II.
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Actions on the Heart and Circulation,stently used doses which must be regarded as toxic. A marked pressor effect can be obtained in the anesthetised cat with an intravenous dose as low as 50 μg/kg (. et al., 1950). Blood pressure increases in response to each of the components of ergotoxine (23, 24, 25, 26)* (., 1946; . et al., 1968).
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https://doi.org/10.1007/978-94-6300-998-0sage regimen, but contains in addition the elements necessary for construction of the drug-release pattern of the pharmaceutical preparation, e.g., immediate release of initial dose or sustained release kinetics.
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https://doi.org/10.1007/978-3-319-65115-6imals and in man. The topics chosen are: Systemic Toxicity, Effects on Reproductive Processes, Potential Genetic Effects, and Interactions. The nomenclature for ergot derivatives used is that given in Chapter II.
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Transkristallisation und ihre Folgen,ccumulated in this book. It is an attempt at a compact synopsis to help those teaching pharmacology or writing a textbook of pharmacology not to overlook the essential chemical and biological basis of the therapeutically most important compounds and those of their activities which are believed to be
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ected work performed in defined isolated systems in which the interference with specific substrates usually called receptors has been sufficiently proven. We hope that this presentation will contribute to the understanding of the complexity of ergot pharmacology as presented in the following chapter
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Elisabeth Pinart,Marta Puigmulél statement he pointed to the great reliability of some drugs, and in particular of ergot, in causing the uterus to contract, thereby diminishing or preventing postpartum haemorrhage and reducing maternal mortality in childbirth.
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