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Titlebook: Epigenetics: Development and Disease; Tapas K. Kundu Book 2013 Springer Science+Business Media Dordrecht 2013 Cancer and diabetes.Chromati

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https://doi.org/10.1007/978-94-009-6009-1he crystal. This suggested that the tails contributed minimally to chromatin structure. However, . studies have shown that the tails were involved in a range of intra- and inter-nucleosomal as well as inter-fibre contacts. The H4 tail, which is essential for chromatin compaction, was shown to contac
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John P. Kostuik,Robert Gillespieeneration to generation with no alterations in the DNA sequence and represent the epigenetic signal in prokaryotes. DNA methyltransferases are enzymes involved in DNA modification and thus in epigenetic regulation of gene expression. DNA methylation not only affects the thermodynamic stability of DN
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The British Caribbean World: Barbados,up. SAM is biosynthesized by methionine adenosyltransferase (MAT) using two substrates, methionine and ATP. Three distinct forms of MAT (MATI, MATII and MATIII), encoded by two distinct genes (. and .), have been identified in mammals. MATII consists of α2 catalytic subunit encoded by . and β regula
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https://doi.org/10.1007/978-3-662-39557-8and fertilization of an egg. Germ cells are unique in their capability to generate new organisms, and extra caution has to be taken to secure the correct inheritance of genetic and epigenetic information. Male germ cells are epigenetically distinct from somatic cells and they undergo several importa
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https://doi.org/10.1007/978-3-662-39563-9s a series of steps in which cells are commited towards the myogenic lineage, undergo expansion to give rise to myoblasts that differentiate into multinucleated myotubes, and mature to form adult muscle fibers. The commitment, proliferation, and differentiation of progenitor cells involve both genet
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https://doi.org/10.1007/978-3-662-39561-50). Efforts to understanding the mechanisms that extend or shorten lifespan have been made since the early twentieth century. Aging is characteristically associated with a progressive decline in the overall fitness of the organism. Several studies have provided valuable information about the molecul
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https://doi.org/10.1007/978-3-662-39558-5igher order of chromatin organization is established during development and dynamically maintained throughout the life span. Developmental mechanisms are conserved in bilaterians and hence they have body plan in common, which is achieved by regulatory networks controlling cell type specific gene exp
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https://doi.org/10.1007/978-3-662-39562-2ng many fundamental cellular processes. Extensive research into the mechanisms governing transcription by Pol I has revealed an intricate set of control mechanisms impinging upon rRNA production. Pol I-specific transcription factors guide Pol I to the rDNA promoter and contribute to multiple rounds
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