书目名称 | Epigenetics: Development and Disease |
编辑 | Tapas K. Kundu |
视频video | |
概述 | Role of genome organisation as a basic platform of different epigenetic phenomena in the pathophysiological context.Epigenetic regulation of transcription Epigenetic contribution in development.Epigen |
丛书名称 | Subcellular Biochemistry |
图书封面 |  |
描述 | Epigenetics is the phenomenon which fine tunes the processes associated with life, beyond that which is specified by the sequence of the genetic material; DNA. The covalent modification of DNA, DNA associated histones, several non histone proteins as well as non coding RNA coherently operate to establish the epigenetic regulation of gene expression in physiological and pathophysiological conditions. This volume presents contributions from worldwide experts presenting their research and findings, including: the evolution of epigenetic machineries from archaea to higher eukaryotes; role of epigenetics in development and transcription regulation; epigenetic landscape of human disease; a chemical biology approach to understanding epigenetic phenomena; exploration of different small molecules as epigenetic therapies.This volume is aimed at students and researchers of chromatin biology and epigenetics and will also be of interest to a broader pharmaceutical audience. |
出版日期 | Book 2013 |
关键词 | Cancer and diabetes; Chromatin dynamics; Epigenetic therapy; Gene expression; Stem cell differentiation |
版次 | 1 |
doi | https://doi.org/10.1007/978-94-007-4525-4 |
isbn_softcover | 978-94-017-7996-8 |
isbn_ebook | 978-94-007-4525-4Series ISSN 0306-0225 Series E-ISSN 2542-8810 |
issn_series | 0306-0225 |
copyright | Springer Science+Business Media Dordrecht 2013 |