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Titlebook: Epigenetics of Infectious Diseases; Walter Doerfler,Josep Casadesús Book 2017 Springer International Publishing AG 2017 bacterial infectio

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Discoveries in Molecular Genetics with the Adenovirus 12 System: Integration of Viral DNA and Epigeted viral genomes become de novo methylated in specific patterns. Inverse correlations between promoter methylation and activity were described for the first time in this system and initiated active research in the field of DNA methylation and epigenetics. Today, promoter methylation has been recogn
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Epigenetic Programming by Microbial Pathogens and Impacts on Acute and Chronic Disease,ial genome that control gene expression in their progeny cells. Microbes can also stimulate heritable changes in the host epigenome via infection-associated alterations to host epigenetic determinants including DNA methylation, histone modifications, chromatin-associated complexes, and noncoding RNA
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Epigenetic Phase Variation in Bacterial Pathogens,r the virulence of a different range of bacterial pathogens of DNA methyltransferases other than Dam has been identified. This leads to new understanding of possible origins and occurrence of heterogeneity and virulent phenotypes in clonal populations. The contribution of new technologies to explore
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Epigenetics of Malaria Parasites,nization will be described. Finally, the promise of epigenetic regulators as targets of novel antimalarial drugs will be addressed. Collectively, these topics provide insight into the unique biology of . spp. and highlight the areas where additional research is necessary for an increased understandi
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