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Titlebook: Epigenetics and Gene Expression in Cancer, Inflammatory and Immune Diseases; Barbara Stefanska,David J. MacEwan Book 2017 The Editor(s) (i

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书目名称Epigenetics and Gene Expression in Cancer, Inflammatory and Immune Diseases
编辑Barbara Stefanska,David J. MacEwan
视频video
概述Explores epigenetics from the wide-angle view of epigenomics.Features detailed methods sections which include data analyses, troubleshooting, and feasibility in different experimental settings.Include
丛书名称Methods in Pharmacology and Toxicology
图书封面Titlebook: Epigenetics and Gene Expression in Cancer, Inflammatory and Immune Diseases;  Barbara Stefanska,David J. MacEwan Book 2017 The Editor(s) (i
描述This practical collection examines methodologies originating from the benefits of genome-wide approaches to studying epigenetics, which has opened the emerging field of epigenomics. Focusing on the areas of cancer, inflammatory and autoimmune disorders, chapters discuss three main components of the epigenome and their role in the regulation of gene expression and present a detailed method section specific to studying each component, including data analyses, troubleshooting, and feasibility in different experimental settings. The main topics are high-throughput and targeted methods for DNA methylation analysis, nucleosome position mapping, studying epigenetic effects of gut microbiota, optical imaging for detection of epigenetic aberrations in living cells, methods for microRNA, and histone code profiling. Written for the .Methods in Pharmacology and Toxicology. series, the book includes the kind of detail and implementation advice to encourage success in the lab. .Authoritative and easily applicable, Epigenetics and Gene Expression in Cancer, Inflammatory and Immune Diseases aims to provide pharmacologists, molecular biologists, bioinformaticians, and toxicologists with a vital bac
出版日期Book 2017
关键词DNA methylation; Histone covalent modifications; Non-coding RNA mechanisms; Epigenomics; Nucleosome posi
版次1
doihttps://doi.org/10.1007/978-1-4939-6743-8
isbn_softcover978-1-4939-8289-9
isbn_ebook978-1-4939-6743-8Series ISSN 1557-2153 Series E-ISSN 1940-6053
issn_series 1557-2153
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
The information of publication is updating

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Methods in Pharmacology and Toxicologyhttp://image.papertrans.cn/e/image/313236.jpg
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American Cinema and Cultural Diplomacyer include enrichment-based method, Methylated DNA Immunoprecipitation (MeDIP), paired with microarray technology and next generation sequencing, and sodium bisulfate-based techniques including Infinium HumanMethylation450 BeadChip (Illumina 450 K) and Reduced Representation Bisulfite Sequencing (RR
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https://doi.org/10.1007/978-94-6300-576-0n the absence of gene sequence alterations through epigenetic modifications such as DNA methylation at cytosine–guanine (CpG) dinucleotides. Due to decreasing costs associated with genomic sequencing, it is becoming more common to screen the DNA methylome to obtain comprehensive information regardin
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https://doi.org/10.1057/9781137463609ithin DNA is important to understanding the potential epigenetic mechanisms of gene regulation during various environmental exposures and diseased states. Targeted nucleosome mapping is a convenient method to map nucleosome positions at a specific genomic locus. In this method, mononucleosomal DNA i
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https://doi.org/10.1007/978-3-030-45435-7rome-associated mutations in genes encoding key enzymes of intermediary metabolism. Here, we provide an outline for the synthesis of cell-permeable forms of the cellular metabolites (.)-2-hydroxyglutarate and (.)-2-hydroxyglutarate, and their application for the inhibition of α-ketoglutarate-depende
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Bruce Tucker,Priscilla L. Waltontions, thus altering the expression of critical genes in pathologic processes, for example in metabolic syndrome. Fermentation end products, especially butyrate and LPS (lipopolysaccharides), the latter being cell-wall components of gram-negative bacteria, have been suggested as bioactive metabolite
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