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Titlebook: Enzymology and Molecular Biology of Carbonyl Metabolism 6; Henry Weiner,Ronald Lindahl,T. Geoffrey Flynn Book 1997 The Editor(s) (if appli

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Inhibition of Human Class 3 Aldehyde Dehydrogenase, and Sensitization of Tumor Cells that Express Sevated levels of this enzyme can account for intrinsic, transient acquired, and stable acquired, resistance to the oxazaphosphorines on the part of malignant cells (Sreerama and Sladek, 1993a,b, 1994; Rekha et al., 1994; Sreerama et al., 1995). Resistance to the oxazaphosphorines mediated by ALDH-3
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Enzymology and Molecular Biology of Carbonyl Metabolism 6
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Lionella Scazzosi,Paola Branduini Hyatt, et al., 1992; Watterson, et al., 1954; McCaffery, et al., 1991; 1992; McCaffery and Dräger, 1993; 1994; 1995; Dräger and McCaffery, 1995). This is clearly seen during the anteroposterior patterning of the trunk (Marsh-Armstrong, et al., 1994) in the Zebrafish, ., in which an endogenous gradi
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Kénel Délusca,Christopher R. Bryantevated levels of this enzyme can account for intrinsic, transient acquired, and stable acquired, resistance to the oxazaphosphorines on the part of malignant cells (Sreerama and Sladek, 1993a,b, 1994; Rekha et al., 1994; Sreerama et al., 1995). Resistance to the oxazaphosphorines mediated by ALDH-3
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Sameen Ruqia Imadi,Alvina Gul Kazirentiation; ALDH-1 and, especially, ALDH-2 catalyze the oxidation of ethanol-derived acetaldehyde to acetate, a detoxifying reaction; ALDH-3 catalyzes the oxidation of 4-hydroxynonenal and other aldehydic products of lipid peroxidation to their corresponding acids, also a detoxifying reaction; and A
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