Titlebook: Enzyme Kinetics in Drug Metabolism; Fundamentals and App Swati Nagar,Upendra A. Argikar,Donald J. Tweedie Book 2014 Springer Science+Busine

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CONE

Irreversible Enzyme Inhibition Kinetics and Drug–Drug InteractionsThis chapter describes the types of irreversible inhibition of drug-metabolizing enzymes and the methods commonly employed to quantify the irreversible inhibition and subsequently predict the extent and time course of clinically important drug–drug interactions.

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沉默

https://doi.org/10.1007/978-3-031-51000-7to understanding enzyme kinetics is having a clear grasp of the meanings of “enzyme” and “catalysis.” Catalysts are reagents that can increase the rate of a chemical reaction without being consumed in the reaction. Enzymes are proteins that form a subset of catalysts. These concepts are further explored below.

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Fundamentals of Enzyme Kineticsto understanding enzyme kinetics is having a clear grasp of the meanings of “enzyme” and “catalysis.” Catalysts are reagents that can increase the rate of a chemical reaction without being consumed in the reaction. Enzymes are proteins that form a subset of catalysts. These concepts are further explored below.

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Swati Nagar,Upendra A. Argikar,Donald J. TweedieIncludes clear explanations of fundamentals for correct application.Contains key notes, experiences and implementation advice from.Covers relevant and current topics including Drug Metabolizing Enzyme

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Methods in Molecular Biologyhttp://image.papertrans.cn/e/image/313091.jpg

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978-1-4939-6046-0Springer Science+Business Media, LLC 2014

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Enzyme Kinetics in Drug Metabolism978-1-62703-758-7Series ISSN 1064-3745 Series E-ISSN 1940-6029

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