| 书目名称 | Enzyme Kinetics in Drug Metabolism |
| 副标题 | Fundamentals and App |
| 编辑 | Swati Nagar,Upendra A. Argikar,Donald J. Tweedie |
| 视频video | |
| 概述 | Includes clear explanations of fundamentals for correct application.Contains key notes, experiences and implementation advice from.Covers relevant and current topics including Drug Metabolizing Enzyme |
| 丛书名称 | Methods in Molecular Biology |
| 图书封面 |  |
| 描述 | .Drug metabolism and transport are very important facets within the discipline of pharmaceutical sciences, with enzyme kinetic concepts utilized regularly in characterizing and modeling the disposition and elimination of drugs. .Enzyme Kinetics in Drug Metabolism: Fundamentals and Applications. focuses on very practical aspects of applying kinetic principles to drug metabolizing enzymes and transporters. Divided into five convenient sections, topics include the fundamental principles of enzyme kinetics, the kinetics of oxidative and conjugative drug metabolizing enzymes and drug transporters, modeling approaches for both drug metabolizing enzymes and transporters including novel systems biology approaches, understanding of variability both experimental and interindividual (pharmacogenomic), and case studies that provide real life examples of applying these principles. Written in the successful .Methods in Molecular Biology. series format, chapters include introductions to their respective topics especially suitable for the novice, in some cases step-by-step, readily reproducible protocols, and insights to help with troubleshooting and avoiding known pitfalls with extensive cross re |
| 出版日期 | Book 2014 |
| 关键词 | drug metabolism; drug transporters; enzyme kinetic models; enzyme kinetics; kinetic analysis; transporter |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-62703-758-7 |
| isbn_softcover | 978-1-4939-6046-0 |
| isbn_ebook | 978-1-62703-758-7Series ISSN 1064-3745 Series E-ISSN 1940-6029 |
| issn_series | 1064-3745 |
| copyright | Springer Science+Business Media, LLC 2014 |
发表于 2025-3-21 18:28:53
