Titlebook: Enzymatic Reactions in Organic Media; A. M. P. Koskinen (Professor of Organic Chemistry) Book 1996 Chapman & Hall 1996 Resol.organic chemi

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New enzymatic properties in organic media,aqueous media without focusing on the mechanistic aspects of this phenomenon (Oyama et al., 1981; Yokozeki et al., 1982). Not until a fundamental study of a large number of biocatalysts had been undertaken (see Klibanov, 1986, for a review) was enzymatic catalysis in non-aqueous media accepted and recognized as a general phenomenon.

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Productivity of enzymatic catalysis in non-aqueous media: New developments,es. Hence the region-and stereospecificity of enzymes and, in particular, the dependence of these characteristics on the reaction conditions and the reaction media employed have been actively investigated in the last few years (see other chapters of this book for an up-to-date review).

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Book 1996ng matter, exemplified by the first examples of organic chemistry through the synthesis of urea from inorganic substances by Liebig, was accepted as the birth of organic chemistry, and thus also of organic synthesis. Although the early developments in organic synthesis closely followed the pursuit o

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al of living matter, exemplified by the first examples of organic chemistry through the synthesis of urea from inorganic substances by Liebig, was accepted as the birth of organic chemistry, and thus also of organic synthesis. Although the early developments in organic synthesis closely followed the

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https://doi.org/10.1007/978-1-4613-9898-1d as being very expensive, fragile catalysts that present substantial problems in handling and downstream processing, i.e. hardly the sort of reagent one would consider for use in industrial organic synthesis. Conventional wisdom also held that enzymes are very substrate- and reaction-specific (the one enzyme—one reaction—one substrate paradigm).

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Large-scale enzymatic conversions in non-aqueous media,d as being very expensive, fragile catalysts that present substantial problems in handling and downstream processing, i.e. hardly the sort of reagent one would consider for use in industrial organic synthesis. Conventional wisdom also held that enzymes are very substrate- and reaction-specific (the one enzyme—one reaction—one substrate paradigm).

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https://doi.org/10.1007/978-1-4757-0103-6lars. The quest for more efficient, more specifically targeted drugs will place a growing demand on enantiopure materials. The rapid pace of development is evident from the fact that of the 95 best selling drugs in the USA in 1994, 36 single-isomer drugs were new chemical entities approved between 1990 and 1993.