| 书目名称 | Environmentally Friendly Alkylphosphonate Herbicides | | 编辑 | Hong-Wu He,Hao Peng,Xiao-Song Tan | | 视频video | | | 概述 | Presents the design and development of pyruvate dehydrogenase complex (PDHc) inhibitors as effective novel herbicides.Introduces the systematical approach to develop novel alkylphosphonates with desir | | 图书封面 |  | | 描述 | .This book presents essential research on a class of environmentally friendly alkylphosphonate herbicides. This class of herbicides acted as a competitive inhibitor of the pyruvate dehydrogenase complex (PDHc) to control weeds. The bioreasoning and systematic approach, from basic research to field tests of candidate compounds, are introduced. The basic research covers the molecular design, chemical synthesis, biological activities evaluation, structure-activity relationship analysis and structural optimization. Subsequently, the book reviews the biochemistry of PDHc inhibitors, the selectivity between mammals and plants, and the mechanism of herbicidal activity of novel alkylphosphonates as selective PDHc inhibitors. Field trials for selected alkylphosphonate candidates as herbicides are also included. This book provides a sound basis for the rational design and development of novel herbicides as effective PDHc inhibitors with good enzyme-selective inhibition of plant PDHc between mammals and plants. These studies take full advantages of the low toxicity and low residual impact of selective PHDc inhibitors to design an effective and environmentally friendly herbicide. This book is | | 出版日期 | Book 2014 | | 关键词 | Alkylphosphinates; Alkylphosphonates; Biorational design; Caged Bicyclic Phosphates; Clacyfos; Cyclic Pho | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-662-44431-3 | | isbn_softcover | 978-3-662-51284-5 | | isbn_ebook | 978-3-662-44431-3 | | copyright | Chemical Industry Press, Beijing and Springer-Verlag Berlin Heidelberg 2014 |
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发表于 2025-3-21 17:42:12
