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Titlebook: Environmental Hygiene II; Norbert H. Seemayer,Wolfgang Hadnagy Conference proceedings 1990 Springer-Verlag Berlin Heidelberg 1990 Atmosphe

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Genotoxicity of Airborne Suspended Matter Determined by in Vitro and in Vivo Short-Term Assaystegy, at the first step a combination of in vitro tests detecting point mutations in bacteria as well as chromosome damage in mammalian cells is proposed. It is specifically stressed that after a positive response in vitro the next assays should be conducted in vivo. At this step mouse bone marrow micronucleus assay is most recommended.
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https://doi.org/10.1007/978-1-4615-6823-0ens there is little concordance between carcinogenicity and mutagenicity of metal compounds in bacteria. In mammalian call mutagenicity assays, all tested inorganic carcinogens are (weak) mutagens (Miyaki et al., 1979).
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The Medical Institute of Environmental Hygiene at the University of Düsseldorf: A Center of Environmes became necessary because heavy air pollution occured during the fifties in large cities and industrialized regions. The level of already high atmospheric pollution further increased during smog episodes leading to concentrations of sulfur dioxide and airborne particulates in the range of today’s
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