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Titlebook: Engineering and Physical Approaches to Cancer; Ian Y. Wong,Michelle R. Dawson Book 2023 The Editor(s) (if applicable) and The Author(s), u

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https://doi.org/10.1057/978-1-137-36537-8cancer cells – resilient subpopulations contributing to chemoresistance and disease recurrence. We summarize key studies used to profile cell forces, cytoskeletal mechanics, and a number of other cell variables (i.e., morphology, migration, proliferation) that are important in cancer progression. Th
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Financialization of Commodity Markets,tumor undergo drastic changes and exert abnormal physical restraints and forces that consequently hinder the efficacy of tumor therapeutics. Therefore, understanding the causes of biophysical abnormalities of tumors and the functional consequences will be beneficial for developing new therapeutic st
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https://doi.org/10.1007/978-0-387-28290-9their isolation and subsequent research difficult. Improving our understanding of CTC biology and the underlying molecular and biophysical mechanisms contributing to metastasis, organotropism, and other clinically relevant parameters will generate a more accurate and comprehensive understanding of t
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2199-2584 Thus, we envision that this book will be suitable for faculty, postdoctoral fellows, and advanced graduate students across medicine, biological sciences, and engineering. We also anticipate this book will be of978-3-031-22802-5Series ISSN 2199-2584 Series E-ISSN 2199-2592
发表于 2025-3-29 13:43:49 | 显示全部楼层
Mechanobiology of Collective Cell Migration in 3D Microenvironments,nspired analyses based on order parameters and phase transitions. Further, we examine the interplay of metabolism and phenotypic heterogeneity in collective migration. We then review the extracellular matrix and new modalities for mechanical characterization of 3D biomaterials. We also explore epith
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Collective Cellular Phase Transitions in Cancer,e abstracted to generalized state variables, including density, cell shape constraints, and fluctuations, which allow phase diagrams to be constructed to aid in predicting behavior. In this chapter, we review both experimental evidence and theoretical frameworks toward understanding multicellular co
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Biophysical and Biochemical Mechanisms Underlying Collective Cell Migration in Cancer Metastasis,c to cancer. We present a detailed discussion on different mathematical and computational modeling frameworks—discrete, hybrid, and continuum—which helps in revealing different aspects of multicellular migration.
发表于 2025-3-30 02:35:35 | 显示全部楼层
Hallmarks of an Aging and Malignant Tumor Microenvironment and the Rise of Resilient Cell Subpopulacancer cells – resilient subpopulations contributing to chemoresistance and disease recurrence. We summarize key studies used to profile cell forces, cytoskeletal mechanics, and a number of other cell variables (i.e., morphology, migration, proliferation) that are important in cancer progression. Th
发表于 2025-3-30 07:24:23 | 显示全部楼层
Physical Regulations of Cell Interactions and Metabolism in Tumor Microenvironments,tumor undergo drastic changes and exert abnormal physical restraints and forces that consequently hinder the efficacy of tumor therapeutics. Therefore, understanding the causes of biophysical abnormalities of tumors and the functional consequences will be beneficial for developing new therapeutic st
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