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Titlebook: Engineering and Physical Approaches to Cancer; Ian Y. Wong,Michelle R. Dawson Book 2023 The Editor(s) (if applicable) and The Author(s), u

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书目名称Engineering and Physical Approaches to Cancer
编辑Ian Y. Wong,Michelle R. Dawson
视频video
概述Describes physical aspects of cancer from the molecular to the tissue level via quantitative image analysis.Highlights early career investigators and underrepresented minority scientists.First volume
丛书名称Current Cancer Research
图书封面Titlebook: Engineering and Physical Approaches to Cancer;  Ian Y. Wong,Michelle R. Dawson Book 2023 The Editor(s) (if applicable) and The Author(s), u
描述.Engineering and Physical Approaches to Cancer. addresses the newest research at this interface between cancer biology and the physical sciences. Several chapters address the mechanobiology of collective and individual cell migration, including experimental, theoretical, and computational perspectives. Other chapters consider the crosstalk of biological, chemical, and physical cues in the tumor microenvironment, including the role of senescence, polyploid giant cells, TGF-beta, metabolism, and immune cells. Further, chapters focus on circulating tumor cells and metastatic colonization, highlighting both bioengineered models as well as diagnostic technologies. Further, this book features the work of emerging and diverse investigators in this field, who have already made impressive cross-disciplinary scientific contributions. .This book is designed for a general audience, particularly researchers conversant in cancer biology but less familiar with engineering (and vice-versa). Thus, we envision that this book will be suitable for faculty, postdoctoral fellows, and advanced graduate students across medicine, biological sciences, and engineering. We also anticipate this book will be of
出版日期Book 2023
关键词cancer progression; cancer therapy; cell fate; cancer cells; Tumor microenvironment; Cancer biology; Physi
版次1
doihttps://doi.org/10.1007/978-3-031-22802-5
isbn_ebook978-3-031-22802-5Series ISSN 2199-2584 Series E-ISSN 2199-2592
issn_series 2199-2584
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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Physical Regulations of Cell Interactions and Metabolism in Tumor Microenvironments,sis accounting for over 90% of cancer-associated mortality. Elucidating the process of tumor progression in the primary tumor is important to the understanding of the sequence of events that gives rise to late stage/metastatic cancer. The primary tumor microenvironment (TME) is a dynamic, heterogene
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,Biophysical Regulation of TGFβ Signaling in the Tumor Microenvironment,sis. The tumor microenvironment experiences dynamic changes in composition and mechanical properties, including alignment of matrix components and variations in the stiffness of the stroma, during cancer progression and recent studies have started to elucidate how these changes govern TGFβ signaling
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Engineering Approaches in Ovarian Cancer Cell Culture,n cancer (OC) biopsies have provided crucial information about the heterogeneity of cancer cell assemblies and their various tumor microenvironments (TMs). Translating this information into tumor biology for the discovery of new treatments could be accomplished by the engineering tissue culture mode
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Biophysical Properties and Isolation of Circulating Tumor Cells,the fluid environment, the small fraction of CTCs that are able to resist destruction and elimination have the potential to form metastatic colonies and can therefore be considered metastatic precursors. CTC survival in the circulatory system is dependent on a number of factors including interaction
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