| 书目名称 | Engineered Zinc Finger Proteins | | 副标题 | Methods and Protocol | | 编辑 | Joel P. Mackay,David J. Segal | | 视频video | | | 概述 | Chapters from nearly all of the top research groups in the field.Sections on zinc finger nucleases, one of the most exciting tools for gene therapy and genome engineering in the past decade.Includes s | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | Among the many types of DNA binding domains, C2H2 zinc finger proteins (ZFPs) have proven to be the most malleable for creating custom DNA-binding proteins.In Engineered Zinc Finger Proteins: Methods and Protocols, expert researchers from some of the most active laboratories in this field present detailed methods, guidance, and perspectives.The volume contains sections covering the engineering of ZFPs, methods for the creation, evaluation, and delivery of artificial transcription factors (ATFs), methods for the creation and evaluation of zinc finger nucleases (ZFNs), and a collection of the several applications and assays beyond ATFs and ZFNs, including zinc finger transposases and ChIP-seq methodology amongst other subjects.Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.Comprehensive and cutting-edge, Engineered Zinc Finger Proteins: Methods and Protocols aims to aid both seasoned practitioners and new investigators with its vital met | | 出版日期 | Book 2010 | | 关键词 | Artificial transcription factors; DNA; DNA binding domains; Designer ZFPs; ZFP construction; Zinc finger | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-60761-753-2 | | isbn_softcover | 978-1-4939-5751-4 | | isbn_ebook | 978-1-60761-753-2Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Springer Science + Business Media, LLC 2010 |
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发表于 2025-3-21 17:08:26
