Titlebook: Endothelin Receptors and Signaling Mechanisms; David M. Pollock,Robert F. Highsmith Book 1998 Springer-Verlag Berlin Heidelberg 1998 Activ

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Endothelin Modulation of Renal Sodium and Water Transport,e thought ET-1 was primarily an endothelial cell-derived product (hence its name), we now know that ET-1 is actually a family of peptides that are produced by a tremendous variety of cell types. Furthermore, ET-1 has a broad spectrum of biological actions affecting multiple cell types, many of which

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Mechanisms of Endothelin-Induced Mitogenesis and Activation of Stress Response Protein Kinases,mitogenic response to growth factors. To understand ET-induced mitogenesis it is critical to understand how G-protein-coupled receptors activate this kinase cascade since it appears that this cascade transduces signals from cell surface receptors to the nucleus, thus altering the transcription of ge

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