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Titlebook: Endothelial Signaling in Development and Disease; Mirko HH Schmidt,Stefan Liebner Book 2015 Springer Science+Business Media New York 2015

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发表于 2025-3-21 18:36:25 | 显示全部楼层 |阅读模式
书目名称Endothelial Signaling in Development and Disease
编辑Mirko HH Schmidt,Stefan Liebner
视频video
概述Comprehensive compendium of the vascular signalosome in developmental cardiovascular physiology.Special emphasis on the current knowledge of crosstalk between the pathways.Written by foremost authorit
图书封面Titlebook: Endothelial Signaling in Development and Disease;  Mirko HH Schmidt,Stefan Liebner Book 2015 Springer Science+Business Media New York 2015
描述This book surveys healthy and diseased vascular systems in a multitude of model organisms and systems. It explores a plethora of functions, characteristics, and pathologies of the vascular system such as angiogenesis, fibroblast growth factor signaling, lymphangiogenesis, junctional signaling, the extracellular matrix, vascular permeability, leukocyte extravasation, axon guidance factors, the angiopoietin system, and chronic obstructive lung disease. Following a preface from leading researcher Dr. Holger Gerhardt, the text is divided into three sections- the first examining the development of the vascular system in a variety of contexts, the second delving into its homeostatic characteristics, and the third discussing its pathophysiologies. The sixteen chapters, which represent international clinical and research perspectives, highlight the importance of molecular and signaling pathways for translational basic science and clinical medicine. Additionally, the text explores new and exciting fields in vascular biology research. Comprehensive in both content and approach, Vascular Signaling in Health and Disease is ideal for graduate students, researchers, and clinicians interested in
出版日期Book 2015
关键词Angiogenesis; VEGF; endothelial; hypoxia; signaling; vascular; Systems Biology
版次1
doihttps://doi.org/10.1007/978-1-4939-2907-8
isbn_softcover978-1-4939-4545-0
isbn_ebook978-1-4939-2907-8
copyrightSpringer Science+Business Media New York 2015
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发表于 2025-3-21 20:41:52 | 显示全部楼层
Development and Differentiation of the Lymphatic Vascular System molecular mechanisms involved in lymphatic endothelial cell identity, embryonic and postnatal lymphatic development and maturation. Knowledge of the underlying molecular mechanisms controlling lymphatic vessel biology may lead to targeted treatments to improve patient care in the future.
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Gabriele Bellenberg,Wolfgang Böttcherendence between the spatial and temporal localization of early angioblasts and their arterial-venous specification has gained some interest and is one focus of this review. Furthermore, we discuss the complex network of genetic interactions that play a role in arterial-venous specification.
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https://doi.org/10.1007/978-3-8349-3744-5ndent effects on the induction of angiogenic and vasoactive factors are described. Together, this chapter aims to provide an overview on how coagulation factor signaling is involved in physiologic and pathologic processes.
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Junctional Signaling in Endothelial Cells in several vascular pathologies. The molecular basis of such defects starts to be recognized and delineates endothelial cell-to-cell junctions as possible pharmacological targets for therapeutic interventions.
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