Titlebook: Endocrine Disorders in Thalassemia; Physiopathological a Sebastiano Andò (Head of Endocrine Physiopathology Book 1995 Springer-Verlag Berli

可互换

Thalassemia and Endocrinopathies: Multicenter Study of 3092 PatientsData regarding the prevalence of endocrine dysfunction in patients with β-thalassaemia major are limited [1, 2], We report the results of a collaborative study of endocrine complications in a large series of patients with β-thalassemia major followed in pediatric and hematology departments throughout Italy.

发牢骚

978-88-470-2185-3Springer-Verlag Berlin Heidelberg 1995

Vulnerable

范围广

祖先

Joanne Garde-Hansen,Hannah Gristl data are available on secondary amenorrhoea (SA), which is a common sequela in transfusion-dependent thalassaemic patients, occurring in 15–25% of Italian thalassaemic patients [3, 13]. Similar figures are available for the United Kingdom [8].

violate

https://doi.org/10.1007/978-3-030-19511-3reased absorption from the gastrointestinal tract, with deleterious effects on internal organs and tissues [2, 7–9]. With modern treatment and longer survival, endocrine dysfunction assumes greater importance [1, 3–5]. This study was carried out in an attempt to correlate such dysfunction with pathologic findings in major endocrine organs.

冷淡一切

Plasma Growth Hormone-Binding Protein and Liver Receptor in Thalassemic Patientsulin-like growth factor I (IGF.) activity is markedly reduced [1–5]. Therefore, the cause of the growth defect is likely to be at the GH receptor or post-receptor level: in either case it would lead to impairment of GH-induced generation of IGF..

GROVE

招待

Adrenaline