Titlebook: Emerging Targets in Antibacterial and Antifungal Chemotherapy; Joyce A. Sutcliffe,Nafsika H. Georgopapadakou Book 1992 Routledge, Chapman

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Interrupt Handling Architectures,d type II based on their ability to catalyse single- or double-strand cleavages, respectively; in addition type II enzymes have an energy requirement satisfied by ATP. In bacteria, topoisomerase II is often referred to as bacterial gyrase. . contains two type I topoisomerases, the TopA and TopB prot

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Emerging Targets in Antibacterial and Antifungal Chemotherapy

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Emerging Targets in Antibacterial and Antifungal Chemotherapy978-1-4615-3274-3

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Historical Perspectives of Approaches to Antibiotics Discoveryntibiotics, however, declined, sharply thereafter, precipitating strategic changes. Mechanism-based or target-directed screening, utilization of rare microorganisms and unusual culture conditions, and introduction of gene technology to modify antibiotic productivity have been among the major changes