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Titlebook: Electrophysiological Analysis of Synaptic Transmission; Nicholas Graziane,Yan Dong Book 2016 Springer Science+Business Media New York 2016

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书目名称Electrophysiological Analysis of Synaptic Transmission
编辑Nicholas Graziane,Yan Dong
视频video
概述A practical guide to electrophysiological manipulations and assays in brain research.A best-practices guide for collecting and interpreting data.Intended for senior undergraduates and above?.Includes
丛书名称Neuromethods
图书封面Titlebook: Electrophysiological Analysis of Synaptic Transmission;  Nicholas Graziane,Yan Dong Book 2016 Springer Science+Business Media New York 2016
描述Electrophysiological methods are used at nearly all levels of biological research today. From basic science investigation to bringing new drugs to market, electrophysiology is an indispensable research technique that provides essential insights into cellular and molecular functions. This work is intended to be a practical guide for understanding and using contemporary electrophysiological manipulations and assays in brain research. New researchers attempting to learn electrophysiological techniques are confronted with a lack of adequate guiding resources. Currently, most electrophysiology-based research knowledge is passed on by experienced individuals to others within the same laboratory. But, this master-apprentice scenario has many inherent difficulties, as it is both a time intensive process and also leads to incomplete knowledge transfer, or even superstitious and maladaptive practices. Few external guiding resources exist for a budding researcher who wishes to gain the skills necessary to conduct responsible and competent electrophysiology research. Dr. Yan Dong, an expert in utilizing electrophysiological techniques for brain research with fifteen years of experience, and Pe
出版日期Book 2016
关键词analysis; brain; electrophysiology; methods; patch-clamp; synapse
版次1
doihttps://doi.org/10.1007/978-1-4939-3274-0
isbn_softcover978-1-4939-8009-3
isbn_ebook978-1-4939-3274-0Series ISSN 0893-2336 Series E-ISSN 1940-6045
issn_series 0893-2336
copyrightSpringer Science+Business Media New York 2016
The information of publication is updating

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Amplitudeon potential amplitudes, field potential amplitudes, postsynaptic current/potential amplitudes, and steady-state current amplitudes. Like many electrophysiological measurements, technical considerations for precise calculations are important. These technical considerations are addressed at the end of this chapter.
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The Essence of the Person-Centered Approachod of action potential firing; a depolarizing potential can increase the probability that an action potential is triggered, while a hyperpolarizing potential can hold the neuron at a membrane potential below threshold (Fig. .).
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