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Titlebook: Eicosanoids and Radiation; Peter Polgar Book 1988 Kluwer Academic Publishers, Boston 1988 cancer.cancer research.cell.cell culture.hormone

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Prostaglandins and Radiation in Cell Culture,gning experiments with fewer confounding variables. As one might expect, the cell biology of prostaglandin production and treatment has been extensively characterized in cultured cells. The cell culture approach also has been invaluable in our understanding of radiation biology, but the literature o
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Effects of Gamma Irradiation on Prostaglandin Biosynthesis and Metabolism: Intact Tissues,ulting in a wide range of effects (1,2), potentially either harmful or protective. Ionizing radiation has been shown to produce changes in prostaglandin production by a variety of tissues (3,4); however the precise mechanisms of such alterations and the role of prostaglandins in the patho-physiologi
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Radiation-Induced Alterations in Cyclooxygenase Product Release: An Overview,platelet aggregatory (TXA2, PGG2 and PGH2) (10–14) and anti-aggregatory properties (PGE2 and PGI2) (15–18) may play a role in radiation-induced tissue injury. This hypothesis is based on the observation that radiation exposure results in tissue injury (19–35) and tissue injury is associated with the
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Effect of Ultraviolet Radiation on Eicosanoid Metabolism of Cells in Culture,on, pigmentation, carcinogenesis, local and systemic immune suppression, aging and Vitamin D metabolism. In addition, such radiation can produce cutaneous disease in individuals rendered abnormally photosensitive by the presence of exogenous drugs and chemicals or endogenous substances such as porph
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Effects of Ultraviolet Radiation on Eicosanoid Metabolism in Intact Skin,f knowledge which has accumulated about eicosanoids and their important role as mediators of cutaneous inflammation, including UV-induced cutaneous changes. In this chapter, we will review the known effects of UV radiation on cutaneous eicosanoid metabolism,
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Protection against Ionizing Radiation with Eicosanoids, the pathogenesis of inflammation. Participation of PGs as chemical mediators in the regulation of immune responses and inflammation are increasingly apparent (1–3). The antagonistic properties of PGs have been implicated in a variety of symptoms resulting from exposure to ionizing radiation. Post i
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Protection of Radiation Damage by Eicosanoids-Clinical Studies,ch have been shown to influence metastases and growth but also suppression of the host. (1–11). Radiation therapy of cancer can lead to local tumor control and potential cure. Recent investigations have shown an increase in prostaglandin production and release in cell and animal models by radiation.
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