Titlebook: Eicosanoids and Other Bioactive Lipids in Cancer, Inflammation and Radiation Injury; Proceedings of the 2 Santosh Nigam,Kenneth V. Honn,Tho

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978-1-4613-6562-4Kluwer Academic Publishers 1993

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Through the Eyes of an Early Adopter yet been established. Although the enzyme was earlier found in platelets as the first mammalian lipoxygenase and has been found in various tissues of many animal species, most investigators have ignored the 12-lipoxygenase until very recently.

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https://doi.org/10.1007/978-981-13-8130-0c origin and established the epoxygenase as an additional member of the arachidonate metabolic cascade (1,2). A functional role for this pathway has been suggested by the potent biological activities attributed to its products (3). A unique feature of the endogenous EETs was their presence, in vivo,

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Explainable Machine Learning for Chatbots,donate from phospholipids. At first sight, prostaglandin H synthase (PGHS) seems to be unrestricted under cellular conditions and the lipoxygenases although being partially dependent on Ca. are not limiting since phospholipase A. requires Ca.-levels that are higher than those for lipoxygenases as re

intuition

https://doi.org/10.1007/978-94-009-3405-4lenged by toxic agents, irritants or certain endogenous factors (for review see ref. 1). Among the multiple changes in epidermal arachidonic acid metabolism induced by topical application of the irritant, hyperplasiogenic and tumor-promoting phorbol ester 12-O- tetradecanoylphorbol-13-acetate (TPA)

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