Titlebook: Effects of Mineral Dusts on Cells; Brooke T. Mossman,Raymond O. Bégin Conference proceedings 1989 Springer-Verlag Berlin Heidelberg 1989 A

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Bronchoalveolar Lavage Cells in Occupational Exposure to Mineral Fibersosure are among the most extensively studied, but several problems remain open. In our institution, workers occupationally exposed to mineral fibers represent approximately one third of over 300 subjects investigated by BAL since 1983.

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MEN

Mutagenicity of Asbestos and Erionite in a , Tester Strain of TA102ange (SCE) (Livingston et al. 1980; Babu et al. 1981) asbestos has produced negative results in most of the short-term genotoxicity tests for the detection of genetic effects. As a consequence, Hesterberg and Barret (1985) have postulated an epigenetic mechanism of asbestos carcinogenicity.

Bricklayer

Bricklayer

Conference proceedings 1989ebec, Canada. The emphasis of the N. A. T. O. Advanced Research Workshop was the use of cell and organ culture and lavage cell populations obtained from man and laboratory animals to elucidate cellular and molecular events occur­ ring after their interaction with fibrous and nonfibrous particulates,

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https://doi.org/10.1007/978-1-4419-9890-3 Histopathologic studies in animals indicate that the effect of increased dust retention is increased penetration of dust into the walls of small airways. Again this is true for both inert and toxic dusts (McFadden et al 1986b; Gilks et al 1988).

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Data Monitoring Committees (DMCs)for production, consumption, and application data). Concern about the potential health hazard of these minerals has arisen due to their fibrous nature and extensive application as asbestos substitutes (Bignon .., 1980).