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Titlebook: ESKAPE Pathogens; Detection, Mechanism Siddhardha Busi,Ram Prasad Book 2024 The Editor(s) (if applicable) and The Author(s), under exclusiv

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https://doi.org/10.1007/978-3-662-34512-2organisms produce a variety of VFs, including antibiotic resistance genes, biofilms, and toxins, which enable them to survive in hostile environments and evade host immune defenses. They have a mobile genetic makeup that allows them to acquire and exchange antibiotic resistance genes, which favor an
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https://doi.org/10.1057/9781137404565in combination with adjuvants are in clinical trials. In recent years, antibiotic adjuvants used against ESKPE pathogens showed promising results as the development of resistance towards multiple agents is less. Also, the toxicity of drugs used in single therapy can be minimized when synergistic eff
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https://doi.org/10.1007/978-90-313-7379-6mics. In search of novel antibacterial and antibiofilm agents, several synthetic and semi-synthetic drugs are being considered for efficient management of chronic microbial diseases. Nevertheless, several factors such as biodegradability issues, toxicity, and less absorptivity limit their candidatur
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