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Titlebook: ECAT Assay Procedures A Manual of Laboratory Techniques; European Concerted A Jørgen Jespersen,Rogier M. Bertina,F. Haverkate Book 1992 Spr

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,Thrombin—antithrombin III complexes,rious activation peptides are released. Fragments F. are split off from prothrombin by the prothrombokinase complex. Specific immunoassays have been developed to determine the concentration of these peptides in plasma.
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Tissue type plasminogen activator antigen (t-PA Ag),the blood by endothelial cells and then rapidly cleared by the liver. The secreted form, a single-chain glycoprotein composed of 530 amino acids (70 kD), can be converted by plasmin or kallikrein into a double-chain form with one disulphide bond.
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Plasminogen activator inhibitor antigen,ith these assays is limited. The presence in plasma of several distinct forms of PAI-1, and the fact that the PAI-1 antigen assays developed to date measure these forms with different efficacy, render interpretation and comparison of PAI-1 antigen data more complicated. Four distinct forms of PAI-1
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Book 1992nique cooperation between experts from more than 60 institutes in 12 European countries, brought together by the ECA T (European Concerted Action on Thrombosis and Disabilities) under the auspices of the Commission of the European Communities in Brussels, Belgium. The ECAT, which was initiated in 19
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The activated partial thromboplastin time (APTT),ll as shortening the test, the presence of an activator has increased the precision and reproducibility of the results by eliminating the variable effects of contact with glass surfaces previously encountered with non-activated PTT methods.
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Euglobulin clot lysis time,viewed ECLT results from a number of workers and showed that their technique of euglobulin fractionation resulted in a product containing variable amounts of procoagulant proteins, all plasma plasminogen, but which contained only traces of antiplasmin activity..
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