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Titlebook: Drugs between Research and Regulations; Proceedings of the 5 C. Steichele (Medizinischer Direktor),U. Abshagen Conference proceedings 1985

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Extending Istio with WebAssembly,t of the therapy to the patient. A clinical trial can be contrasted with an observational study where one undertakes a retrospective record review in an attempt to determine the benefit of therapy which has been administered to patients. In general, the use of observational studies to establish the value of therapies is not reliable.
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The role of carcinogenicity studies in risk assessments opened the view to possible long-term consequences of certain forms of chemotherapy. Furthermore, for drugs in general which are intended for longer-term use, the question of carcinogenicity has become, from the regulatory point of view, most decisive for the fate of a new product.
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https://doi.org/10.1007/978-1-4842-9348-5f pharmacological studies possible within the set ethical limits. These limits themselves, however, are not directly related to the progress in medical research. They are determined by public opinion in a given country at a given time and are not likely to change rapidly.
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Rauwolfia derivatives and breast cancer: how do we know when we have the answers?ugh it has some properties in common with those of the multicentre trial, seems to have received rather less attention or even to have been almost entirely neglected by some of those whom it most concerns is the combination of information from studies that are spread out not only in space but also in time.
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Conference proceedings 1985of a gathering which so clearly bore his imprint as Chairman of the Scientific Program Committee. His sudden passing away is deeply regretted by all of us: organizers, speakers and participants. We greatly respect him for his exceptional abilities, his impact on science and his qualities as a human
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