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Titlebook: Drugs between Research and Regulations; Proceedings of the 5 C. Steichele (Medizinischer Direktor),U. Abshagen Conference proceedings 1985

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My Story, humans are exposed for an extended period of time. Thus, the intention was not to study the acute toxic reactions, but rather the slowly developing lesions related to organ-directed toxicity, accumulation of the test substance or its metabolites in certain organs, functional and structural changes
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Writing,d ., i.e. in whole rodent and nonrodent animals. Certain rules and regulations exist that govern the form of performance of chronic toxicity testing for different sectors of our chemical world, for example, OECD regulations for testing of chemicals, EEC and FDA regulations for testing pharmaceutical
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Outro,cceed, now and again, in thwarting their deliberations and obscuring their aims. The issue of Guidelines for the Clinical Investigation of Drugs is a case in point. They are hailed by some and condemned by others and nine tenths of the problem is that the one party really has little idea what the ot
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