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Titlebook: Drugs and the Elderly; Perspectives in Geri J. Crooks,I. H. Stevenson Book 1979 J. Crooks and I. H. Stevenson 1979 absorption.analgesics.an

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To the Stars through Dimensions and Factsnd its associated pathophysiological changes have been shown to alter responsiveness to drugs, as a result of either altered pharmacokinetics (for review, see Crooks, O’Malley and Stevenson, 1976), or altered pharmacodynamics (Castleden .. 1977).
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https://doi.org/10.1007/978-1-4471-1921-0illness increases with age, and in recurrent depressive illness, the frequency of episodes also increases. The diagnosis of a depressive illness in the elderly patient generally presents few problems, although the appearance of pseudodementia may complicate the clinical picture in a small number of
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Verwendung von ISV-Applikationen effect of increasing age on drug activity was the subject of a series of early studies conducted in the 1940s by K. K. Chen and his colleagues at Eli Lilly. These investigators found that increased age in experimental animals was associated with increased sensitivity to the effects of alcohol (Chen
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https://doi.org/10.1007/978-3-658-24590-0ese drugs not only are more common in this age group, but also may vary in quality compared with those described in the young. Thus, paradoxical excitement (Gibson, 1966), nocturnal restlessness (Exton-Smith, 1967) and imbalance following barbiturates (MacDonald and MacDonald, 1977) occur with such
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Criteria for the design of an animal-holding facility for ageing animals as illustrated by the Wolfsmodels findings might emerge which are of general applicability in a geriatric context. An interest in gerontology has led to the establishment in the University of Hull of a colony of rats to satisfy the research needs of the Hull group and also the group led by Professor D. Bellamy of Cardiff University.
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