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Titlebook: Drugs and the Developing Brain; Antonia Vernadakis (Associate Professor),Norman We Book 1974 Plenum Press, New York 1974 biology.brain.chi

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https://doi.org/10.1007/978-1-4757-2545-2use large changes take place in a short period of time. Thus, the brain of rats is mature by 21 days of age, although certain events (for example, myelination and glial growth) take place over a longer period of time. (For discussions of the ontegeny of the blood-brain barrier, see Davson, 1973 and Saunders and Bradbury, 1973).
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Selective Depression of Organotypic Bioelectric Activities of CNS Tissue Cultures by Pharmacologic ativities by decreasing availability of Ca. to the neural tissue; and b) those which depress synaptic network discharges by selective effects at inhibitory receptor sites, e.g., hyperpolarization or increased membrane conductance, in mimicry of inhibitory transmitters.
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Maturation of the Blood-Brain and Blood-CSF Barriersuse large changes take place in a short period of time. Thus, the brain of rats is mature by 21 days of age, although certain events (for example, myelination and glial growth) take place over a longer period of time. (For discussions of the ontegeny of the blood-brain barrier, see Davson, 1973 and Saunders and Bradbury, 1973).
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https://doi.org/10.1007/978-1-4684-3063-9biology; brain; childhood; development; developmental biology; drug; drugs; evaluation; pharmacology; researc
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978-1-4684-3065-3Plenum Press, New York 1974
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A. Aeschlimann,C. Mermod,J. F. Grafes can generate progressively more complex organotypic bioelectric activities as they mature in culture (e.g. Fig. 1; Crain, 1966, 1969; Crain and Bornstein, 1964; Crain and Peterson, 1964, 1967). The present studies emphasize the pharmacologic properties of these CNS explants, and they illustrate t
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