| 书目名称 | Drugs and the Developing Brain |
| 编辑 | Antonia Vernadakis (Associate Professor),Norman We |
| 视频video | |
| 丛书名称 | Advances in Behavioral Biology |
| 图书封面 |  |
| 描述 | The thalidomide tragedy which occurred slightly more than a decade ago made public officials and the general public acutely aware of the teratogenic potential of drugs. Although specialists in pharmacology and developmental biology had been studying this problem many years before, this catastrophic episode triggered the passage of legislation which required that information about the teratogenicity of drugs be produced before the drugs could be available to the general public. Gross deformities in man produced by drugs are frequently difficult to reproduce in experimental animals and the changes which are produced in other animals are frequently not translatable to humans. The problem of evaluating the potential that drugs have to produce gross malformations is small, however, compared to the evaluation of subtle but permanent behavioral effects which drugs may exert upon the developing organism. Nevertheless, many experimental studies in recent years indicate that subtle biochemical changes produced by drugs on brain tissue during critical periods of fetal or early post natal maturation may become manifest subsequently as behavioral deviations in early childhood or adolescence. H |
| 出版日期 | Book 1974 |
| 关键词 | biology; brain; childhood; development; developmental biology; drug; drugs; evaluation; pharmacology; researc |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-1-4684-3063-9 |
| isbn_softcover | 978-1-4684-3065-3 |
| isbn_ebook | 978-1-4684-3063-9Series ISSN 0099-6246 |
| issn_series | 0099-6246 |
| copyright | Plenum Press, New York 1974 |
发表于 2025-3-21 18:16:46
