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Titlebook: Drugs and Immune Responsiveness; Book 1979

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楼主: Anagram
发表于 2025-3-23 13:01:59 | 显示全部楼层
Approaches to prevention and treatment of drug allergy,10 to 15 per cent untoward reactions of hospitalised patients to one or the other drug administered to them; among these 40 to 50 per cent are felt to be of allergic nature (Klein .., 1972), which leaves us with an overall incidence of about 5 per cent of allergic reactions to drugs in a population of hospitalised patients.
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Federal Republic of Germany (West Germany),ssions is not in doubt, its mode of action is still unknown. The ability of D-PAm to chelate copper and other heavy metals is the basis for its use in Wilson’s disease and in lead poisoning, but there is no evidence that this has any relevance to its therapeutic effect in rheumatoid arthritis.
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Federal Republic of Germany (West Germany), in man both . and . (Tripodi .., 1973; Pabst and Crawford, 1975; Huskisson .., 1976; Ivanyi and Lehner, 1977) and in animals (Renoux and Renoux, 1973; Fischer .., 1975). Enhancement of lymphocyte proliferation . by mitogens or the mixed leucocyte culture reaction has been reported when levamisole w
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Federal Republic of Germany (West Germany),ects in different ways. On the one hand, they may enhance non-specific effector mechanisms operative in the resistance of infectious agents and to neoplastic cells. On the other hand, they may non-specifically increase specific immune responses elicited by the recognition of antigenic determinants.
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Federal Republic of Germany (West Germany),ergic drug-induced rèactions either during therapy or in circumstances of occupational exposure to the drug. The majority of adverse reactions to drugs are not immunologically mediated but can be understood on the basis of direct toxicity owing to overdosage, to side effects and to secondary effects
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Federal Republic of Germany (West Germany),here these are likely to associate or conjugate to carrier macromolecules .. It would seem worthwhile therefore first to outline current knowledge about the various factors that are known to influence allergic responses to natural and experimental sensito-gens in general, before briefly considering
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