Titlebook: Drugs Targeting B-Cells in Autoimmune Diseases; Xavier Bosch,Manuel Ramos-Casals,Munther A Khamash Book 2014 Springer Basel 2014 Cryoglobu

大火

Vulnerary

Daniel B. Cornfield,Randy Hodsonidisciplinary therapeutic approach. Treatment of sicca manifestations is symptomatic (topical therapies like saliva substitutes and preservative-free artificial tears), while the management of extraglandular features is tailored to the specific organs involved. The use of biological drugs targeting

矛盾

拘留

Nadya Araujo Guimarães,Marcia de Paula Leitedous interest around the role of B-cells in the early inflammation, autoimmunity, and subsequent fibrosis both in animal and human models. There have been promising results from B-cell depletion therapy in clinical trials in both SSc and IIM. This review will concentrate on the role of B-cells in pa

发出眩目光芒

BLANC

话

Consequence

Building an International Sociology of Workditions, evidence on the use of these therapies is restricted to rituximab and it mainly relies on individual case reports or short series. In general, the underlying pathophysiology of the disease and/or the successful use of biological agents with a different mechanism of action seem to justify th

Assignment

Nadya Araujo Guimarães,Marcia de Paula Leiteiseases such as SLE. Rituximab also has a longer established role in the treatment of B-cell lymphoproliferative disorders and rheumatoid arthritis. In this chapter we review the available data on the safety aspects of B-cell targeted therapies. A common adverse event with this family of agents is i

牲畜栏

Daniel B. Cornfield,Randy Hodsonpire, leaving open the potential for development and regulatory approval of 1 or more “similar” versions of these biologic therapies, termed biosimilars in Europe (BS)—the term that will be used in this chapter—subsequent entry biologics in Canada, or follow-on-biologics in the USA. The development