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Titlebook: Drugs Targeting B-Cells in Autoimmune Diseases; Xavier Bosch,Manuel Ramos-Casals,Munther A Khamash Book 2014 Springer Basel 2014 Cryoglobu

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书目名称Drugs Targeting B-Cells in Autoimmune Diseases
编辑Xavier Bosch,Manuel Ramos-Casals,Munther A Khamash
视频video
概述Written and edited by leading international experts with long clinical experience.Provides comprehensive background and practical information for scientists, clinicians and pharmaceutical companies.Im
丛书名称Milestones in Drug Therapy
图书封面Titlebook: Drugs Targeting B-Cells in Autoimmune Diseases;  Xavier Bosch,Manuel Ramos-Casals,Munther A Khamash Book 2014 Springer Basel 2014 Cryoglobu
描述.This book provides a detailed overview of B-cell directed therapies in patients with rheumatic and systemic autoimmune diseases, including rheumatoid arthritis, systemic lupus erythematosus, Sjögren syndrome, ANCA-associated vasculitis and cryoglobulinemia. Organ-specific autoimmune diseases are discussed with respect to the use of B-cell directed therapies in neurological autoimmune diseases and autoimmune cytopenias. Situations in which B-cell targeted therapy may be indicated are identified, thereby offering comprehensive support for therapeutic decisions on the basis of the latest published evidence. The book also offers a valuable reference tool for rheumatologists, internists, nephrologists, immunologists, and all specialists involved in the multidisciplinary care of patients with rheumatic and systemic autoimmune diseases..
出版日期Book 2014
关键词Cryoglobulinemia; Inflammatory myopathies; Rheumatoid arthritis; Sjögren syndrome; Systemic lupus erythe
版次1
doihttps://doi.org/10.1007/978-3-0348-0706-7
isbn_ebook978-3-0348-0706-7Series ISSN 2296-6056 Series E-ISSN 2296-6064
issn_series 2296-6056
copyrightSpringer Basel 2014
The information of publication is updating

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Targeting B Cells in ANCA-Associated Vasculitides,mall and medium-sized vessels. Glomerulonephritis in AAV is typified by focal necrosis, crescent formation, and few or no immunoglobulin deposits. In vitro and animal evidence suggests that ANCA play a pathogenic role in AAV. Specific gene expression signatures are reported to predict long-term prog
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