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Titlebook: Drugs During Pregnancy; Methodological Aspec Bengt Källén Book 2016 Springer International Publishing Switzerland 2016 Epidemiological meth

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发表于 2025-3-21 18:22:01 | 显示全部楼层 |阅读模式
书目名称Drugs During Pregnancy
副标题Methodological Aspec
编辑Bengt Källén
视频videohttp://file.papertrans.cn/284/283182/283182.mp4
概述Extensively discusses the research problems involved in the study of risks associated with drug use during pregnancy.Based on more than 50 years’ experience of research in the field.Illustrates proble
图书封面Titlebook: Drugs During Pregnancy; Methodological Aspec Bengt Källén Book 2016 Springer International Publishing Switzerland 2016 Epidemiological meth
描述.This book addresses methodological aspects of epidemiological studies on maternal drug use in pregnancy. Discussing the existing sources of error and how they can produce incorrect conclusions, it examines various epidemiological techniques and assesses their strengths and weaknesses. These refer both to the identification of outcomes (with special emphasis on congenital malformations) and to the types of exposure (drug use). ..Further, the book discusses the problem of confounding and how to handle it, and provides a simple introduction to statistics. Special situations, e.g. different types of parental exposure, are examined. Lastly, the book discusses pharmacovigilance and the information problem, concluding with a short list of aspects to consider when one wants to evaluate a published paper in the field. .Though the book is primarily intended for pharmacologists, gynecologists and obstetricians, it will benefit all doctors working in perinatal care..
出版日期Book 2016
关键词Epidemiological methods; Pregnancy outcome; Congenital malformations; Confounding factors; Exposure; phar
版次1
doihttps://doi.org/10.1007/978-3-319-40697-8
isbn_softcover978-3-319-82158-0
isbn_ebook978-3-319-40697-8
copyrightSpringer International Publishing Switzerland 2016
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Ethics and Reproductive Biology, or by linkage with registers of prescriptions. Each method has its limitations which are discussed in the chapter. The least reliable method is retrospective ascertainment perhaps months after the delivery when a recall bias may occur, and often a large percentage of nonparticipants may cause furt
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M, R and Some Scale Estimators,ip it. Odds ratios and risk ratios are presented and how their statistical significance can be evaluated, including the concept of confidence interval. Methods of adjusting for confounders, survival analyses, and power analyses are briefly described. Finally, a discussion is made of the meaning of a
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Gordon Betcherman,Douglas Rebnerder to identify specific effects. This refers both to drug use and to outcome, e.g., malformations. The chapter discusses these problems separately for drugs and for malformations..The idea with lumping (adding together related groups) is to get larger numbers. On the other hand, one runs the risk
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Gordon Betcherman,Douglas Rebne verify or reject the observation. Such studies must have enough power to detect the suggested association. Some examples are described in the chapter. Meta-analyses try to summarize a number of different studies, but this methodology is often not suitable for epidemiological studies, for instance,
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Workers, Managers, and Technological Change can then be the object of detailed investigation. An example is the monitoring based on the Swedish Medical Birth Register which is described. The available information in the literature on data on use of drugs during pregnancy and pregnancy outcome should be summarized for the benefit of the nonsp
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