Titlebook: Druggable Lipid Signaling Pathways; Yasuyuki Kihara Book 2020 Springer Nature Switzerland AG 2020 lipids.GPCR.drug discovery.disease.trans

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Elizabeth F. Churchill,Nina Wakefordlecular family is primarily represented by the bioactive molecules ceramide, sphingosine, and sphingosine 1-phosphate (S1P). The flux of sphingolipid metabolism at both the subcellular and extracellular levels provides multiple opportunities for pharmacological intervention. The caveat is that pertu

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Introduction to Work Life 2000 Workshopsr medicinal purposes continues to increase worldwide. Since the discovery of Δ.-tetrahydrocannabinol (THC) as the primary psychoactive component of cannabis over 50 years ago, substantial effort has been directed toward detection of endogenous mediators of cannabinoid activity. The discovery of anan

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Conclusions From the First 12 Workshopsspects of how cells respond to their extracellular environment. In addition, they play critical roles in regulating membrane trafficking and lipid transport within the cell. The class I phosphoinositide kinases which generate the critical lipid signal PIP. are hyperactivated in numerous human pathol

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https://doi.org/10.1007/978-3-030-50621-6lipids; GPCR; drug discovery; disease; translational research

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