| 书目名称 | Drug-Induced Liver Toxicity | | 编辑 | Minjun Chen,Yvonne Will | | 视频video | | | 概述 | Includes cutting-edge techniques for the study of DILI.Contains key implementation advice from the experts.Features detail essential for labs, from basic research through to clinical action | | 丛书名称 | Methods in Pharmacology and Toxicology | | 图书封面 |  | | 描述 | This book provides a comprehensive view of the methodologies used for the study of liver toxicity encountered throughout the whole life cycle of a drug, from drug discovery, to clinical trial, post-marketing, and even clinical practice. Organized into six sections, the first section introduces the mechanisms contributing to drug-induced liver toxicity. The second and third section explore in silico and in vitro approaches used to help mitigate hepatotoxicity liability at the early stages of drug development. The fourth section describes methodologies applied in regulatory processes, including preclinical studies, clinical trials, and post-marketing surveillance. The fifth section discusses clinical hepatotoxicity. Emerging technologies are examined in the final section. As a volume in the Methods in Pharmacology and Toxicology series, chapters include the kind of expert advice that will lead to optimal results. .Authoritative and practical, .Drug-InducedLiver Toxicity. serves all those who aim to improve assessment and understanding of hepatotoxic potentials of new medications and marketed drugs..Chapter 30 is open access under a CC BY 4.0 license via link.springer.com. . | | 出版日期 | Book 2018 | | 关键词 | Acute liver failure; Drug development; Regulatory processes; Preclinical and clinical studies; Hepatotox | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4939-7677-5 | | isbn_softcover | 978-1-4939-9256-0 | | isbn_ebook | 978-1-4939-7677-5Series ISSN 1557-2153 Series E-ISSN 1940-6053 | | issn_series | 1557-2153 | | copyright | Springer Science+Business Media, LLC, part of Springer Nature 2018 |
The information of publication is updating
|
|
发表于 2025-3-21 19:04:40
