| 书目名称 | Drug Target miRNA | | 副标题 | Methods and Protocol | | 编辑 | Marco F. Schmidt | | 视频video | | | 概述 | Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts | | 丛书名称 | Methods in Molecular Biology | | 图书封面 |  | | 描述 | .This volume provides a concise and technical discussion of recently developed approaches to overcome challenges, such as pharmacodynamics and pharmacokinetics difficulties, in miRNA drug discovery. These strategies cover anti-sense agents targeting miRNA that are applied in advanced formulations or are chemically optimized to increase delivery; small molecule miRNA modulators to overcome anti-sense agents’ limitations; general enhancers of miRNA maturation; and Argonaute 2 protein and its pharmacokinetic parameters. Written in the highly successful .Methods in Molecular Biology .series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..Cutting-edge and thorough, .Drug Target miRNA: Methods and Protocols. is a valuable resource for anyone interested in the ever-evolving field of miRNA drug discovery... . | | 出版日期 | Book 2017 | | 关键词 | drug discovery; pharmacodynamics; pharmacokinetics; small molecule miRNA modulators; anti-sense agents; D | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4939-6563-2 | | isbn_softcover | 978-1-4939-8236-3 | | isbn_ebook | 978-1-4939-6563-2Series ISSN 1064-3745 Series E-ISSN 1940-6029 | | issn_series | 1064-3745 | | copyright | Springer Science+Business Media, LLC, part of Springer Nature 2017 |
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发表于 2025-3-21 19:40:58
