Titlebook: Drug Safety Evaluation; Methods and Protocol Jean-Charles Gautier Book 2017Latest edition Springer Science+Business Media LLC 2017 immunohi

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P. Jermann,A. Soller,A. Lesgoldoped over the last decade for this purpose. Most approaches for the assay, however, measure cells with a . mutant phenotype in erythrocytes from the peripheral blood, with the mutations causing the phenotype being difficult to determine directly. This chapter describes a procedure for detecting muta

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P. A. Kirschner,R. L. Martens,J. W. Strijbosin biomonitoring, and in fundamental research. Its sensitivity and range of application are increased by the incorporation of an extra step, after lysis of agarose-embedded cells, in which the DNA is digested with lesion-specific endonucleases (DNA repair enzymes of bacterial or phage origin). Enzym

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L. Lipponen,K. Hakkarainen,S. Paavola assessment. Induced pluripotent stem cell-derived cardiomyocytes (iPSCs) can be used for this purpose as these cells display similar electrochemical properties to primary cardiomyocytes and beat reliably and in synchronicity in culture. Here we describe a method for measuring the contractility of i

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