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Titlebook: Drug Resistance; William N. Hait Book 1996 Kluwer Academic Publishers 1996 DNA.Drogen.apoptosis.breast cancer.cancer.chemotherapy.drug.dru

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Mechanisms of Clinical Resistance to 5-Fluorouracil Chemotherapyact that profound biological effects had been observed upon substitution of fluorine for hydrogen in several classes of compounds, it was postulated that fluorine-substituted pyrimidine analogs might display selective antitumor activity.
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0927-3042 This comprehensive volumeshould be of value for basic and clinical scientists who wish to delvemore deeply into this intriguing problem in the laboratory anddevastating problem in the clinic.978-1-4612-8540-3978-1-4613-1267-3Series ISSN 0927-3042 Series E-ISSN 2509-8497
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Human Immunodeficiency Virus Replication in the Presence of Antiretroviral Drugs: Analogies to Antinatologists care for patients with hemophilia and HIV infection, or patients with HIV-associated hematologic disorders, such as immune thrombocytopenia, antiphospholipid antibodies, chronic cytopenias, and thrombotic thrombocytopenic purpura.
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Acquisition of an Antiestrogen-Resistant Phenotype in Breast Cancer: Role of Cellular and Molecular implicated [2]. Estrogens may function as carcinogens and/or cocarcinogens [2,3], but it is their role as promoters of the growth of estrogen-dependent and estrogen-responsive tumors through activation of their nuclear receptors [2] that has provided a rationale for the design of therapeutic strategies, that is, antiestrogens.
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Book 1996leading investigators in thefield have reviewed the most basic mechanisms of drug resistance, andhave proposed ways to modulate resistance. This comprehensive volumeshould be of value for basic and clinical scientists who wish to delvemore deeply into this intriguing problem in the laboratory anddevastating problem in the clinic.
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