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Titlebook: Drug Receptors and Their Effectors; Biological Council S Nigel J. M. Birdsall Conference proceedings 1981Latest edition Macmillan Publisher

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Adrenocorticotrophin-(1-24)-tetrakosipeptide spans lipid membranes: experiments with liposomes,-(1-24)-tetrakosipeptide (ACTH.) and artificial planar lipid-bilayer membranes was revealed. After addition of ACTH. to one side of the pure lipid membrane, the hormone molecules are adsorbed in a rapid, reversible reaction, whereupon, in a slow reaction, parts of the individual molecules, presumabl
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Biosynthesis and turnover of nicotinic acetylcholine receptors, considered as a lipid bilayer with associated proteins or a two-dimensional micellar array of ordered units. Today most students of plasma membrane structure consider this matter settled in favour of the lipid bilayer, and the overall focus of today is on the dynamic aspects of plasma membrane; the
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The summing up,ed to the cell interior and those already in the interior. The first of these classes is embedded in a membrane and is constrained to act in two dimensions, and it is all too tempting to regard the lipid phase of the membrane as a passive supporting matrix, yet the effects on phospholipid turnover d
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Implantation of hormone receptors: fusion of membrane components with cell membranes,nditions of concentration, polarity, etc., under which the solubilised components would associate properly to produce the functional complex. Thus, crude and purified preparations of receptors were obtained which demonstrated specific binding of antagonists or agonists but failed to demonstrate biol
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Hormonal control of ion permeability of the pancreatic acinar cell membrane mediated by intracellul 1978.). Electrophysiological investigations with several intracellular microelectrodes and extra- and intracellular micro-application of drugs are feasible due to the thinness of the mouse pancreas, allowing easy visualisation of individual cells in the living tissue (Iwatsuki and Petersen, 1978.,
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