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Titlebook: Drug Receptors and Their Effectors; Biological Council S Nigel J. M. Birdsall Conference proceedings 1981Latest edition Macmillan Publisher

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发表于 2025-3-21 17:21:41 | 显示全部楼层 |阅读模式
书目名称Drug Receptors and Their Effectors
副标题Biological Council S
编辑Nigel J. M. Birdsall
视频video
图书封面Titlebook: Drug Receptors and Their Effectors; Biological Council S Nigel J. M. Birdsall Conference proceedings 1981Latest edition Macmillan Publisher
出版日期Conference proceedings 1981Latest edition
关键词drug; receptor; research
版次1
doihttps://doi.org/10.1007/978-1-349-05555-5
copyrightMacmillan Publishers Limited 1981
The information of publication is updating

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Interactions of muscarinic receptors with guanine nucleotides and adenylate cyclase,detailed knowledge of the properties of the binding site, particularly in the brain (Hulme ., 1978; Birdsall ., 1978, 1980.; Galper ., 1977), and despite the identification and characterisation of a plethora of responses elicited by muscarinic agonists in whole cells and tissues (Birdsall and Hulme,
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Implantation of hormone receptors: fusion of membrane components with cell membranes,elling of the underlying mechanisms at the molecular level has been rather slow. Biochemical characterisation of the components required solubilisation of the membrane molecules in detergents, which resulted almost invariably in the loss of biological activity of the receptor-response system. Recons
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Hormonal control of ion permeability of the pancreatic acinar cell membrane mediated by intracellulrmeability responses are mediated by changes in cytosolic ionised calcium concentration (Petersen, 1976, 1980; Bülbring and Tomita, 1977; Putney, 1979). The pancreatic acini would appear to provide a good model for the study of the mechanisms underlying hormonal control of plasma membrane permeabili
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Phosphatidylinositol metabolism and calcium gating in a 5-HT receptor system,onsible for generating intracellular signals such as cyclic AMP or calcium. These two second messengers seem to be associated with the action of a wide range of agonists. The generation of these messengers is mediated through two different types of receptor. The adrenergic system is a good example i
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Interaction of fluorescent analogues of acetylcholine with nicotinic acetylcholine receptors and acs in which the events at the neuromuscular junction may be simulated .. Since this time range is of the order of milliseconds, rapid kinetic techniques have to be employed. Suitable ligands for such studies require the following combination of properties: (1) they must have suitable spectroscopic pr
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