Titlebook: Drug Discovery in Pancreatic Cancer; Models and Technique Haiyong Han,Paul Grippo Book 2010 Springer-Verlag New York 2010 Han.cancer.diagno

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Drug Evaluations in Pancreatic Cancer Culture Systems,bdomen and the lack of overt symptoms before cancer dissemination. Thus, it is critical to have a variety of modeling systems that can be employed to evaluate drug responses/mechanisms while providing a relatively simple format for drug screening. Cell culture serves this purpose. In this context, i

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A New Preclinical Paradigm for Pancreas Cancer,tempts to cure and even contain it. The approach to the patient with pancreas cancer is the same as for any cancer: detect it early, diagnose it accurately and eradicate it through a combination of surgery and chemical and radiotherapies. However, cancer of this organ eludes early detection, runs th

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Zebrafish as a Biological System for Identifying and Validating Therapeutic Targets and Compounds,creatic epithelia into pre-malignant neoplasia and eventually invasive carcinoma. In spite of these advances, effective treatment is still lacking, and the prognosis of most patients diagnosed with pancreatic cancer is dismal. Molecularly targeted agents show great potential for improving treatment