| 书目名称 | Drug Discovery in Pancreatic Cancer | | 副标题 | Models and Technique | | 编辑 | Haiyong Han,Paul Grippo | | 视频video | | | 概述 | This has made the development of pharmacodynamic endpoint assays and the small animal imaging models ever more important.The last two chapters of the book will review the recent developments in this a | | 图书封面 |  | | 描述 | .Pancreatic cancer is the fourth leading cause of cancer death in the United States. Every year, about 33,700 people in the United States will be diagnosed with pancreatic cancer and over 32,000 patients will die from the disease. The median survival of patients with advanced pancreatic cancer is about 6-months. This dismal picture of pancreatic cancer is mainly due to the lack of early diagnosis and effective treatment for patients with advanced disease. To increase the survival rate of pancreatic cancer patients, better tumor markers for diagnosis and new molecular targets for drug development are desperately needed. A lot of effort has been made in searching for pancreatic cancer-causing genes or genes associated with progression of malignant behavior in pancreatic cancer. As a result, alterations in the expression of several cancer-related genes have been identified in pancreatic tumors. The identification and characterization of these cancer-related genes have significantly increased our understanding of pancreatic cancer development, but unfortunately the treatment of pancreatic cancer has not advanced as much in the past 20 years...Over the past decade, tremendous advances h | | 出版日期 | Book 2010 | | 关键词 | Han; cancer; diagnostics; drug discovery; imaging; pancreatic; siRNA | | 版次 | 1 | | doi | https://doi.org/10.1007/978-1-4419-1160-5 | | isbn_softcover | 978-1-4899-8275-9 | | isbn_ebook | 978-1-4419-1160-5 | | copyright | Springer-Verlag New York 2010 |
The information of publication is updating
|
|
发表于 2025-3-21 18:26:04
