Titlebook: Drug Delivery to the Brain; Physiological Concep Margareta Hammarlund-Udenaes,Elizabeth C.M. de Lan Book 20141st edition American Associati

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Drug Delivery to the Brain978-1-4614-9105-7Series ISSN 2210-7371 Series E-ISSN 2210-738X

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Drug Metabolism at the Blood–Brain and Blood–CSF Barriersolism, reviews the molecular and functional evidence for drug-metabolizing enzyme location at both the blood–brain barrier (BBB) and blood–CSF barrier (BCSFB), and discusses their functional significance for modulating cerebral drug delivery and brain toxin exposure.

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Book 20141st editionarriers, the most important being the blood –brain barrier (BBB). Many factors are therefore critical to consider for CNS drug delivery, e.g. active/passive transport across the BBB, intra-brain distribution, and central/systemic pharmacokinetics, to name a few. Neurological disease and trauma condi

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,General Remarks – Allgemeine Hinweise,we will highlight the issues that should be considered when translating basic research towards clinical development. Although it is still unrealistic to expect a magic bullet for exclusive CNS drug delivery, much progress has been made towards successful development of novel treatments for patients with devastating brain diseases.

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