Titlebook: Dopaminergic System Function and Dysfunction: Experimental Approaches; José Antonio Fuentealba-Evans,Pablo Henny Book 2023 The Editor(s) (

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Universitäten im LeistungswettbewerbWe used the software Neurolucida, which allows vector-based 3D reconstruction of both individual neurons and nuclei and offers various analytical tools. The first method involves the use of cyto- or chemo-architectonics to identify boundaries between subdivisions and marking, onto the dendrite being

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https://doi.org/10.1007/978-3-658-25139-0 and DAT dynamics using acute brain slices combined with high-performance liquid chromatography (HPLC) for DA detection along with a modification of a classically used radioactive uptake assay to measure levels of DA uptake. Further examining DAT functions and DA dynamics is key for the development

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Motivation zum Rechtsformwechsel,channel in which they are dependent on each other. We then add random synaptic input to the model to illustrate the hypothesized balanced state in dopamine neurons, which is quite distinct from the balanced state of neocortical pyramidal neurons. We use this model to explain transient bursts and pau

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https://doi.org/10.1007/978-3-658-26620-2eurobiological mechanisms underlying the vulnerability of the adolescent brain because the similarities in behavioral patterns and brain maturation processes with human adolescents. Particularly, both human teenager and adolescent rodents show similar patterns of DA maturation, and dysregulations in

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Severin Johann Lederhilger OPraemg animals to access the activity of the parkinsonian cortico-basal ganglia-thalamo-cortical loop. Given that both the dopaminergic lesion caused by 6-hydroxydopamine, and the quality of the extracellular recordings have temporal dynamics of their own, the relative timing of both procedures is essent

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Ultrastructural Study of Dopaminergic Axon Terminalsed synaptic transmission caused by alterations in proteins expressed at the axon terminal. In order to examine this, electron microscopy can be used, as it allows us to perform detailed analyses of the ultrastructure of dopaminergic terminals. The aim of this chapter is to provide a comprehensive pr

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