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Titlebook: Dopaminergic System Function and Dysfunction: Experimental Approaches; José Antonio Fuentealba-Evans,Pablo Henny Book 2023 The Editor(s) (

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书目名称Dopaminergic System Function and Dysfunction: Experimental Approaches
编辑José Antonio Fuentealba-Evans,Pablo Henny
视频video
概述Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts
丛书名称Neuromethods
图书封面Titlebook: Dopaminergic System Function and Dysfunction: Experimental Approaches;  José Antonio Fuentealba-Evans,Pablo Henny Book 2023 The Editor(s) (
描述.This volume provides a variety of technical approaches to study dopamine system function and dysfunction. Chapters guide readers through dopamine release in .ex vivo. and freely moving animals, multi-recording devices for .in vivo. simultaneous single cell and population activity,  .in silico. modeling of dopamine neurons activity, neuroanatomical approaches, unbiased stereology, ultrastructural analyses of dopaminergic neurons, and axonal innervation. Additionally, chapters also incorporate pharmacological tools to model neuropsychiatric diseases, novel behavioral paradigms to dissect dopamine‘s role in behavior, and functional imaging to follow human dopamine system development. In the .Neuromethods. series style, chapters include the kind of detail and key advice from the specialists needed to get successful results in your laboratory..Comprehensive and cutting-edge, .Dopamine Neurotransmission .aims to be a valuable resource for researchers in various disciplines. .
出版日期Book 2023
关键词optogenetic control; neuropsychiatric models; viral vector strategies; dopamine circuits; in vivo functi
版次1
doihttps://doi.org/10.1007/978-1-0716-2799-0
isbn_softcover978-1-0716-2801-0
isbn_ebook978-1-0716-2799-0Series ISSN 0893-2336 Series E-ISSN 1940-6045
issn_series 0893-2336
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
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Quantifying Dopaminergic Innervation in Rodents Using Unbiased Stereologyases and an inability to provide an absolute number of markers throughout an entire region of interest. Design-based stereology provides an unbiased alternative, as it uses mathematical and statistical principles to form accurate predictions about the distribution of objects in three-dimensional bra
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Dendrites Crossing Borders: Quantifying the Distribution of Individual Substantia Nigra Dopaminergicre its cell body locates. We refer to this as heterotopic dendritic distribution (Montero et al., Front Neural Circuits. 15:769342, 2021). This phenomenon has important implications for individual neurons afferent synaptic integration; insofar dendritic trees extending across different nuclei or sub
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Modeling Pacemaking, Bursting, and Depolarization Block in Midbrain Dopamine Neuronsate a set of coupled nonlinear equations that describe the equivalent circuit that generates the membrane potential, the nonlinear dynamics of channel gating, and a material balance on Ca. ions. The general methodology is conductance-based single-neuron computational models. We begin with Hodgkin-Hu
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The MAM Model to Study the Role of Dopamine in Schizophrenia states, many of which are analogous to those observed in schizophrenia. MAM is a DNA-methylating agent that, when injected at gestational day 17, produces in the adult offspring a constellation of alterations such as anxiety, increased locomotor response to amphetamine injection, increased number o
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