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Titlebook: Dopamine Receptor Agonists; George Poste,Stanley T. Crooke Book 1984 Springer Science+Business Media New York 1984 cardiovascular system.d

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Book 1984tivities in a number of major organ systems, including the central ner­ vous system. the cardiovascular system, the kidney, and the gut. Recent advances in our understanding of the functional role of dopamine, its mechanism of action and the pharmacology of dopaminergic agents have occurred on a bro
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https://doi.org/10.1007/978-3-658-02386-7ors and do not exert significant actions at other adrenoceptors. As discussed in several chapters of this volume, one of the major aims in developing these compounds is for the therapeutic potential they offer in the treatment of various cardiovascular and renal disorders.
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Structure—Activity Relationships of Dopamine Receptor Agonistso be present in mammalian tissue by Goodall (1950a,b, 1951). Blaschko (1957) first suggested an independent physiological role for DA in the periphery. More recently, DA has been identified as a neurotransmitter in the CNS (Carlsson ., 1958; Carlsson, 1959; Goodall and Alton, 1968; Hornykiewicz, 1971).
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Dopamine Receptor Agonists and Hypertensionors and do not exert significant actions at other adrenoceptors. As discussed in several chapters of this volume, one of the major aims in developing these compounds is for the therapeutic potential they offer in the treatment of various cardiovascular and renal disorders.
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Molecular Mechanisms of Vasodilatationleotides, and nitrogen oxide-containing agents. This chapter deals primarily with the latter agents, which include organic nitrates and nitrites, inorganic nitrites, nitroso Compounds, S-nitrosothiols, and nitric oxide.
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