| 书目名称 | Dissecting Regulatory Interactions of RNA and Protein |
| 副标题 | Combining Computatio |
| 编辑 | Marvin Jens |
| 视频video | |
| 概述 | Nominated as an outstanding PhD thesis by Max Delbrueck Center for Molecular Medicine, Germany.Combines concepts and approaches from physics with high-throughput data to model gene regulation and answ |
| 丛书名称 | Springer Theses |
| 图书封面 |  |
| 描述 | .The work described in this book is an excellent example of interdisciplinary research in systems biology. It shows how concepts and approaches from the field of physics can be efficiently used to answer biological questions and reports on a novel methodology involving creative computer-based analyses of high-throughput biological data. Many of the findings described in the book, which are the result of collaborations between the author (a theoretical scientist) and experimental biologists and between different laboratories, have been published in high-quality peer-reviewed journals such as Molecular Cell and Nature. However, while those publications address different aspects of post-transcriptional gene regulation, this book provides readers with a complete, coherent and logical view of the research project as a whole. The introduction presents post-transcriptional gene regulation from a distinct angle, highlighting aspects of information theory and evolution and laying the groundwork for the questions addressed in the subsequent chapters, which concern the regulation of the transcriptome as the primary functional carrier of active genetic information.. |
| 出版日期 | Book 2014 |
| 关键词 | Binding site occupancy; CDR1as; Competing RNA; ELAVL1 HuR; Model of ELAVL1 binding; PAR-CLIP clusters and |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-07082-7 |
| isbn_softcover | 978-3-319-36117-8 |
| isbn_ebook | 978-3-319-07082-7Series ISSN 2190-5053 Series E-ISSN 2190-5061 |
| issn_series | 2190-5053 |
| copyright | Springer International Publishing Switzerland 2014 |
发表于 2025-3-21 17:22:20
