Titlebook: Disruptive Psychopharmacology; Frederick S. Barrett,Katrin H. Preller Book 2022 The Editor(s) (if applicable) and The Author(s), under exc

Instrumental

Classic Psychedelics in Addiction Treatment: The Case for Psilocybin in Tobacco Smoking Cessationo use disorder. I review historical research from the 1950s to 1970s suggesting that classic psychedelics are associated with addiction recovery across pharmacologically distinct drugs of addiction. I then review anthropological reports about ceremonial use of classic psychedelics and epidemiologica

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Psychedelics and Anti-inflammatory Activity in Animal ModelsHT. receptor is the most widely expressed mammalian serotonin receptor and is found in nearly every examined tissue type including neural, endocrine, endothelial, immune, and muscle, suggesting it could be a novel and pharmacological target for several types of disorders. Despite this, the bulk of r

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Psilocybin for the Treatment of Obsessive-Compulsive Disorderse and alternatives merit priority attention. Psilocybin may represent a safe and effective avenue for treatment of individuals affected by this condition. In this chapter we briefly introduce OCD symptoms, epidemiology, as well as relevant hypotheses on the mechanism of disease that may inform treat

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Psychedelics as Novel Therapeutics in Alzheimer’s Disease: Rationale and Potential Mechanismssts psychedelics can exert persisting anxiolytic and antidepressant effects lasting up to several months after a single administration. Data indicate acute subjective drug effects as important psychological factors involved in observed therapeutic benefits. Additionally, animal models have shown an

UTTER

Psilocybin for Trauma-Related Disordersritical need for innovative approaches. We provide an overview of trauma and PTSD and cite literature providing converging evidence of the therapeutic potential of psilocybin for PTSD. No study to date has investigated psilocybin or psilocybin-assisted psychotherapy (PAP) as treatments for PTSD. An

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Effects of Setting on Psychedelic Experiences, Therapies, and Outcomes: A Rapid Scoping Review of thn psychedelic therapies, as well as consistent interest in theorizing about these effects. However, this consensus has yet to generate consistent, prospective, rigorous tests of setting and its complexities. As a result, the field continues to lack understanding or agreement regarding the effects of