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Titlebook: Disruptive Psychopharmacology; Frederick S. Barrett,Katrin H. Preller Book 2022 The Editor(s) (if applicable) and The Author(s), under exc

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Dosing Psychedelics and MDMAly 3,4-methylenedioxymethamphetamine, have received renewed attention in psychiatric research and may be developed into medications for such indications as anxiety, depression, cluster headache, and posttraumatic stress disorder, among others. However, identifying proper doses is crucial. Controlled
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Foundations for Training Psychedelic Therapistsering the disconnected parts of ourselves and reestablishing fundamental trust. The authors then walk through six therapist competencies that describe the root principles of practice, breadth of knowledge, transpersonal perspective, and therapeutic stance of a psychedelic practitioner. This model in
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Ayahuasca for the Treatment of Depression (.), with leaves from a shrub in the coffee family . (.). Mixed with water and boiled for hours or days, it produces a brownish-colored liquid with a strong and characteristic taste. Ayahuasca contains the psychedelic tryptamine N,N-Dimethyltryptamine (DMT), and Monoamine Oxidase Inhibitors (MAOi),
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Psilocybin for the Treatment of Depression: A Promising New Pharmacotherapy Approachral lines of evidence from early-phase experimental trials suggest that serotonergic psychedelics, particularly psilocybin, with therapeutic support show great promise in the treatment of depression with large effect sizes. Neuroimaging data have also revealed the dynamic effects of psilocybin on fu
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Ketamine for Depression: Advances in Clinical Treatment, Rapid Antidepressant Mechanisms of Action, t research into other novel rapid-acting antidepressants – most notably serotonergic psychedelics (SPs) – has also proven promising. Presently, the mechanisms of action of these substances are under investigation to improve these novel treatments, which also exhibit considerable side effects such as
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The Potential of Psychedelics for End of Life and Palliative Caretexts remain limited. In particular, psychological factors such as depression, existential distress, and well-being remain challenging to address with current medications. Here, we review recent research on the use of psychedelics in clinical settings with a particular focus on patients with life-th
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Psychedelic-Assisted Therapy for Substance Use Disorders and Potential Mechanisms of Actionis high unmet need, recent results reporting beneficial outcomes of psychedelic-assisted therapy in SUD are particularly relevant. However, several questions remain with regard to this treatment approach. The clinical mechanisms of action of psychedelic substances in the treatment of SUD are not wel
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