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Titlebook: Directed Enzyme Evolution: Advances and Applications; Miguel Alcalde Book 2017 Springer International Publishing AG 2017 biocatalysis.biom

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Strain Development by Whole-Cell Directed Evolution,r, we summarize recent technological advances and applications of directed evolution in strain development, focusing on the efforts for accelerating evolution workflows, expanding the range of target phenotypes, and facilitating mechanistic understanding of evolved mutations.
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Sprinkler Irrigation Types and Componentsderivatives are, the more complex the synthesis becomes. In this chapter, we summarize the development of an engineered enzymatic platform for synthesis of diverse tryptophan analogs. This endeavor utilizes the tryptophan synthase (TrpS) enzyme, an α.β. heterodimeric protein complex that catalyzes t
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Uniform Irrigation with Sprinklersopment, protein-based compounds represent an important subset among these biomacromolecular drug candidates, ranging from antibodies, anticoagulants, growth factors, hormones, interferons, and interleukins to enzymes. While recombinant gene technology has traditionally played a key role in developme
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Konstruktionsvalidierung durch Simulation,). The complicated catalytic chemistry of Rubisco slows its CO. fixation rate, allows for competitive inhibition by oxygen and permits the production of misfire products that can self-inhibit activity. Significant effort has been invested into better understanding the structure-function details of R
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